Bleomycin injection route before using mayo clinic. Twelve subsequent patients matched for age, dosage of bleomycin, and incidence of pulmonary problems were studied prospectively to determine whether the. Administration of bleomycin via the oropharyngeal aspiration route. It is usually used as a last resort because the shot can cause burning or pain at the site of the injection. Bleomycin is known to cause single, and to a lesser extent, doublestranded breaks in dna. Here are the steps to inserting a pdf file into a word document. To add files from your computer, drag any files or folders into the pdf portfolio workspace or onto a folder, which is available in the left pane. A list of us medications equivalent to bleomycin is available on the website.
Dailymed bleomycin bleomycin sulfate injection, powder. Bleomycin sulfate is an antineoplastic antibiotic isolated from streptomyces verticillus. Bleomycin is inactivated by a cytosolic cysteine proteinase enzyme, bleomycin hydrolase. Cisplatin p, vinblastine v and bleomycin b combination. Rearrange individual pages or entire files in the desired order. Bleomycin is commonly part of combination therapy for cancer treatment. The icon is blank when you insert an object or a file into. What mitomycin looks like and contents of the pack mitomycin powder for solution for injection is a powder which is mixed before injection. These are the best ways to insert any form of content, including pdf into powerpoint.
How to use ole between powerpoint and excel duration. I am working on transfering my plots to a presentation using officer package in r. In in vitro and in vivo experiments, bleomycin has been shown to cause cell cycle arrest in g2 and. In short, one can add images, tables and text into documents from r. Dosages of bleomycin may depend upon the specific indication for its use, and whether other cytotoxic agents are coadministered. Save your presentation powerpoint or keynote as a pdf. It is a clear liquid that is usually injected into a vein. Ways to convert powerpoint into an interactive elearning module. A unit of bleomycin is equal to the formerly used milligram activity. Bleomycin appears to undergo extensive metabolism by a specific cysteine proteinase, bleomycin hydrolase.
Open your powerpoint presentation on the page you want to insert the pdf within. Iintralesional bleomycin in the treatment of ntralesional. Cisplatin p, vinblastine v and bleomycin b combination chemotherapy in recurrent or advanced granulosatheca cell tumours of the ovary. The injection should be made superficially into the mass or into the remaining tumour after surgical reduction. Bleomycin injection contains bleomycin as an active ingredient.
This letter is not intended as a complete description of the benefits and risks related to the use of bleomycin sulfate powder for injection 15,000 iu. Procedures for proper handling and disposal of anti cancer drugs should be utilized. Unfortunately, inserting pdf content is not possible when editing a presentation in powerpoint. A list of us medications equivalent to bleomycin is available on the. This document has been prepared in accordance with standards for workplace safety, which requires the inclusion of all. These are all risk factors that can predispose the patient to bleomycin pulmonary toxicity. Administration precautions caution should be exercised when handling bleomycin for injection. To keep a pdf file as a support document for your presentation insert the entire pdf into the presentation as an object that you can open and view during your presentation. Insert pdf file content into a powerpoint presentation powerpoint. How to convert a pdf to a scorm package in a few seconds. The enzyme is widely distributed in normal tissues with the exception of the skin and lungs, both targets of bleomycin. Bleomycin induced pneumonitis apparently produces dyspnea and fine rales that are in no way different from those produced by infectious pneumonias, or the signs and symptoms produced by primary or metastatic lung disease in some patients. Use our online service to convert pdf to ppt in a heartbeat.
Bleomycin is widely distributed throughout the body with a mean volume of distribution of 17. Bleomycin is an antitumor antibiotic used successfully to treat a variety of. Pharmacokinetics of a single bolus injection of bleomycin in elderly cancer. Tell your doctor if you have ever had an unusual or allergic reaction to bleomycin before receiving bleomycin. Insertembed pdf file in powerpoint 2010 presentation. The tube with cells was added by pi to 50 gml and incubated at 4c in the dark for 30 min. How to put video inside pdf powerpoint templates and. Bleomycin is approved by the fda food and drug administration in the usa, medsafe in new zealand, and similar regulatory authorities in other countries, for the treatment of squamous cell carcinoma of the head and neck, cervix, penis and skin, hodgkin lymphoma and nonhodgkin lymphoma, testicular cancer and malignant pleural effusion. Request permission export citation add to favorites track citation. Bleomycin fda prescribing information, side effects and uses. To embed pdf file in slide, open the slide in which you want to embed file, head over to insert tab and click object. Powerpoint 2016 tutorial inserting objects microsoft. The 2 mg vials are packaged into cartons containing 1, 5 or 10 vials.
The related drug information index provides comprehensive access to all drug information related to a specific drug types of content include full prescribing information, drug summaries, full prescribing information continuing medication education full pi cme, medication guides, risk evaluation and mitigation strategies rems summaries, rems continuing medication education rems cme, and. The underlying assumption is that r is your computational engine and that you are trying to get outputs into powerpoint. In in vitro and in vivo experiments, bleomycin has been shown to cause cell cycle arrest in g2 and in mitosis. The bleomycin for injection 30 units vial should be reconstituted with 2 to 10 ml of the above diluents. Mar 11, 2019 bleomycin is known to cause single, and to a lesser extent, doublestranded breaks in dna. Bleomycin injection works by producing ions which get into dna of cancer cell and prevent its growth. Pdf instruction manuals, guides, and howto articles are a popular way of transferring knowledge. For nonprescription products, read the label or package ingredients carefully. On xray, bleomycin induced pneumonitis produces patchy opacities, usually of the lower lung fields. Fdaapproved bleomycin sulfate for injection, usp for full prescribing information. The information on this website is intended for informational purposes only and is not a substitute for medical advice. Aug, 2019 a unit of bleomycin is equal to the formerly used milligram activity.
This is not usually excessive and settles in the days following treatment. When administered into the pleural cavity in the treatment of malignant pleural effusion, blenoxane acts as a sclerosing agent. Of the patients already treated with intralesional bleomycin injection in our unit after 3,000 treatments, minimal side effects occurred. Bleomycin what names may be used for this medication. The compound is heat stable, has a high melting point, and is freely soluble in organic solvents. As an intrapleural into the pleural cavity the space between the lining of the lung and the chest wall injection. Bleo, blenoxane, nsc125066, blm bleomycin bleeohmicein is a drug that is used to treat many kinds of cancer. This is done to treat a malignant pleural effusion. You insert an object or a file into a document, presentation, spreadsheet, or other microsoft office 2003 or microsoft office xp file. Although nongenital warts are not cancerous, bleomycin injection is sometimes used to kill skin cells, effectively stopping wart growth.
Bleomycin distributes mainly into the tissues of the skin, lungs, kidneys, peritoneum, and lymphatics. Several studies concluded that subsequent fertility is clinically unaffected. Bleomycin belongs to the general group of medicines called antineoplastics. Only select registry of toxic effects of chemical substances rtecs data is presented here. Jun 22, 2010 blenoxane bleomycin sulfate injection is abortifacient but not teratogenic in rabbits at intravenous doses of 1. Steps to convert ppt into elearning using adobe captivate 2017 syed amjad ali swift is an innovative elearning services company that provides endtoend elearning solutions to corporates. Dailymed bleomycin injection, powder, lyophilized, for. It is a mixture of glycopeptide antibiotics containing primarily bleomycin a 2. I compare and contrast three tools for creating and updating powerpoint reports using r. Bleomycin, blenoxane how and why is this medicine given. Physicians in 1800s noted that cancer pts sometimes unexpectedly went into remission after experiencing a viral infection. Bleomycin bleomycin sulfate dose, indications, adverse. Follow these steps to use adobe acrobat to combine or merge word, excel, powerpoint, audio, or video files, web pages, or existing pdfs. Manipulation of microsoft word and powerpoint documents.
The 10 and 20 mg vials are packaged into cartons containing 1 or 5 vials. Bleomycin is given by an intravenous push a rapid infusion into a vein of your hand or arm or through a port or subcutaneously sq. How to convert powerpoint into an interactive elearning. Bleomycingastric cancerproliferation apoptosismigration.
Interactive learning, teaching and evaluation resources created with geogebra can be shared and used by everyone at the geogebra app for powerpoint lets you insert interactive geogebra materials into your presentation. Go to insert tab object double click package in the list of options then the create package dialog. Save money on your prescription by switching to tevas fdaapproved generic version, bleomycin for injection, usp. Velcade must not be administered into your spinal fluid intrathecally. Highlights of prescribing information these highlights do not. Jul 21, 2011 as enquired by the reader, i would like to inform here that our patient did not receive any supplemental oxygen therapy after the administration of bleomycin. Intralesional bleomycin injection south tees hospitals nhs. The benefits and risks of nursing against discontinuing the drug must be weighed carefully. This includes hodgkins lymphoma, nonhodgkins lymphoma, testicular cancer, ovarian cancer, and cervical cancer among others. Bleomycin is the generic name for the trade name drug blenoxane. To insert an object, click object on the insert tab. Bleomycingastric cancerproliferationapoptosismigration. Tumor releases antigens introduced into dendritic cells sentinels of the immune system generates potent antitumor immunity.
This is a quick video tutorial demonstrating how you can package a pow erpoint presentation to cd or usb in powerpoint 20162020102007. A pdf document is filled with all kinds of content, including text or images, that you might want to import elsewhere. Combine documents into one pdf and rearrange pages from within onedrive for business or from sharepoint, word, excel, or powerpoint online. Convert an illustrator vector graphic to a powerpoint. There are no adequate reports or wellcontrolled studies in pregnant women.
Unfortunately, inserting pdf content is not possible when editing a presentation in powerpoint for the web. Bleomycin by injection national library of medicine. Bleomycin also may used for other conditions, as determined by your doctor. In some cases, health care professionals may use the trade name blenoxane when referring to the generic drug name. Key clinical message the evidence supporting therapy with imatinib for. Bleomycin suppresses the proliferation and the mobility of human. Dailymed bleomycin injection, powder, lyophilized, for solution. Always consult your healthcare provider if you have questions or concerns. In the object window that appears, switch to the create from file tab and then click. Prescribing information cubicin daptomycin for injection. Pharmacokinetics of a single bolus injection of bleomycin in elderly. Combine files into a single pdf, insert a pdf into another pdf, insert a clipboard selection into a pdf, or place insert a pdf as a link in another file.
The antibiotic is usually administered via the intratracheal or. Bleomycin for injection may be given by the intramuscular, intravenous, subcutaneous or intrapleuralroutes. Highlights of prescribing information these highlights do not include all the information needed to use blincyto safely and effectively. Bleomycin is injected intralesionally at a dose rate of 0. Most patients will experience some swelling of the birthmark after treatment. Finially i figured out a way to solve this pdf attachment problem on excel. Pulmonary fibrosis can be experimentally induced in small rodents by bleomycin. Bleomycin is injected into warts that have been resistant to other treatments.
Knowledge and time are the 2 most valuable resources in the world that we currently live in and, now, we have many opportunities to. Dosage may be reduced, delayed or discontinued in patients with bone marrow. Predicting the risk of bleomycin lung toxicity in patients with germ. Any changes you make to these geogebra materials are saved in your powerpoint file. It is administered by a healthcare professional as an injection into your vein intravenously, or iv or under your skin subcutaneously, or sc. More and more of my presentations start to use video, and my preferred format for emailingdropboxing decks is pdf, so how do you insert a video in pdf. Bleomycin is classified as an antitumor antibiotic. Find patient medical information for bleomycin injection on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Bleomycin is an anticancer antineoplastic or cytotoxic chemotherapy drug. Insert an object in word or outlook office support. Administration precautions caution should be exercised when handling bleomycin. Bleomycin is a chemotherapy agent commonly used for the treatment of hodgkins lymphoma and. Information for the patient bleomycin 15000 iu powder for solution for injection infusion bleomycin. Supplemental oxygen therapy in bleomycininduced pulmonary.
To do this, you use one of the methods in the following examples. In this post we are covering how to embed a pdf document in the presentation. Sometimes, there is a shape or vector graphic from a popular stock photo site that id like to edit and use in powerpoint. How to convert a pdf file to a scorm package in a few clicks. Discontinuation of bleomycin when documented strongly suspected lung toxicity 1a symptomatic with impaired pfts. Bleomycin interstitial pneumonitis bip has been thought to be. You can either choose one of the files already uploaded on your site or upload a new pdf file. Oxygenexacerbated bleomycin pulmonary toxicity mayo clinic. Intravenous the contents of the 15 units or 30 units vial should be dissolved in 5 ml or 10 ml, respectively, of sodium chloride for injection. Longterm effects of bleomycin on reproductive function are insufficiently studied. Bleomycin sulfate investigated as a drug, mutagen, natural product, reproductive effector, and tumorigen. This may imply on lowering of bleomycin dosage, in particular in the elderly. Create and update powerpoint reports using r displayr. Your doctor will administer bleomycin into a vein or artery, under the skin, into a muscle, directly into the tumour, or into.
Combine or merge files into a single pdf, adobe acrobat dc. Insert pdf content into your presentation either as a picture that shows on your slide, or as a document that you can open during your slide show. Highlights of prescribing information age group dosage. Also there is an option to open the file in new window when the user clicks on the link. Bleomycin for injection prescribing information getwell. Cannot insert object error when inserting pdf files. If youre creating a microsoft powerpoint presentation, you can insert a pdf document by following these steps. Although there is no specific information comparing use of bleomycin in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults. Insert pdf file content into a powerpoint presentation. Steps to convert ppt into elearning using adobe captivate.
In the excel file, head over to the insert tab and then click the object button. Depending on the version of word or outlook youre using, you can insert a variety of objects such as pdf files, excel charts or worksheets, or powerpoint presentations into a word document or an email message by linking or embedding them. Bleomycin is poorly absorbed across the gi tract and must be administered parenterally. Method of administration your doctor will administer bleomycin into a vein or artery, under the skin, into a muscle, directly into the tumour, or into the space surrounding the lungs intrepleural, either by injection or using an infusion. The enzyme is widely distributed in normal tissues with the exception of the skin and lungs, both targets of bleomycin toxicity.
If neither of those two methods work for your needs, you can also add a pdf file into a powerpoint presentation as an action. Velcade is prescribed by a doctor experienced in the use of medications to treat cancer. Place your cursor by clicking on the area where you wish to insert the pdf document. It is used to treat several types of cancer, including cervix and uterus cancer, head and neck cancer, testicle and penile cancer, and certain types of lymphoma. These are the best ways to insert any form of content, including pdf into powerpoint files, online or offline. When administered into the pleural cavity in the treatment of malignant pleural effusion, bleomycin acts as a sclerosing agent.
1092 59 1237 928 439 889 600 975 343 1002 956 1051 983 792 1379 241 601 28 1076 1193 1452 1119 773 750 1184 394 1528 1468 678 518 611 485 1523 1349 1153 566 1209 1051 936 549 779 754 201